Abstract
In the recent past, evidence has accumulated that there is an interesting but obscure relationship between genesis of mast cells and functions of thymus (1). In the present work, the effects of removal and direct antigenic stimulation of thymus on tissue histamine and mast cell contents in various tissues were studied on albino rats. In view of the existence of blood-thymus barrier as postulated by Nossal and Mitchell (2), injections of antigen were given directly into the substance of the gland.
