Abstract
In order to accumulate fundamental data concerning circulatory pharmacological studies using Beagles, vascular responses to 28 drugs of the coronary, renal, mesenteric and femoral vascular beds were investigated. It is expected that there may he qualitative differences among the responses to hydralazine, lobeline, DMPP, nicotine, procaine and TEA of Beagles and those of mongrel dogs reported previously. When peripheral vascular responses to norepinephrine, ACh, adenosine and histamine were examined quantitatively, no significant differences were observed between Beagle and mongrel dogs regarding sensitivities to the four tested drugs.
