The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
STUDIES ON SITES OF ACTION OF ANALGESICS
2. THE EFFECT OF ANALGESICS ON AFFERFNT PATHWAYS OF PAIN
SADAO FUJITAMOTOHIRO YASUHARASHIGERU YAMAMOTOKIKUO OGIU
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1954 Volume 4 Issue 1 Pages 41-51

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Abstract
In the previous report (1), a small dose of morphine, dolantin and ohton (dithienyldimethylbutenylamine) blocked splanchnic afferents in the spinal cord, and vagal afferents in the medulla oblongata, while they did not block afferents of the sciatic nerve. In the present paper, the effect of analgesics on afferent pathways of other nerves was studied, and attention was concentrated mainly upon pain afferents. Furthermore the effect of these drugs on their relay nuclei, reverberating system and centrencephalic integrating mechanism was investigated.
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