The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
A NEW MEASUREMENT OF BLOOD FLOW
AKIRA UENOFUMIO TAKENAKA
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1955 Volume 4 Issue 2 Pages 98-102

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Abstract
The purpose of this communication is to describe a new type of flowmeter for measuring blood flow in living animals. Previously we could not record automatically the quantity of the blood flow continuously by various methods. By means of our measurement (Fig. 1), however, the blood flow can be recorded continuously on the smoked paper of kymograph and the quantity measured with calibration. The principle of our method is, like the method of Fleisch (1) and Moe (2), based on Poiseuille's formula which is represented as follows: V /t= (p1-p2)πr4/8
After the administering heparin to the animal, the blood is allowed to pass through a glass tube connected to cannulae inserted into the exposed vessel. And then the pressure differences at the two points of the tube are recorded by means of a new type of Hg-manometer which was originated by the authors. When the viscosity (η) of the liquid (blood), diameter (r) and length (l) of the tube are constant, the rate of flow (V/t) according to Poiseuille is proportional to the pressure differences (p1-p2) recorded by the above manometer.
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