The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
Vascular Responses of Isolated, Perfused Canine Femoral Arteries and Veins to Vasoactive Substances
Kimiko KAWAIShigetoshi CHIBA
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1986 Volume 41 Issue 4 Pages 537-540

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Abstract
The stainless steel cannula inserting method was used to observe vascular effects of 9 vasoactive substances on the isolated, perfused canine femoral artery and vein. In the vein, the order of potency for inducing vasoconstriction was norepinephrine>histamine=phenylephrine=serotonin>prostaglandin F > ATP > xylazine > tyramine >> KCl. It was demonstrated that the cannula inserting method is useful for observations of venous vascular reactivity.
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