Effects of Efonidipine Hydrochloride on Cholesterol Esterification Mediated by Beta-Very Low Density Lipoprotein in J774 Macrophages

Masaki Kitahara; Kyomi Toyoda; Toshie Yamashita; Mitsuaki Sakashita; Sakuya Tanaka; Yasushi Saito

doi:10.1254/jjp.69.101

Masaki Kitahara, Kyomi Toyoda, Toshie Yamashita, Mitsuaki Sakashita, Sakuya Tanaka, Yasushi Saito

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Keywords: Efonidipine, Macrophage, Cholesteryl ester, β-Very low density lipoprotein, Cyclic AMP

JOURNAL FREE ACCESS

1995 Volume 69 Issue 2 Pages 101-109

DOI https://doi.org/10.1254/jjp.69.101

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Abstract

The effects of efonidipine hydrochloride (efonidipine), a dihydropyridine calcium antagonist, on the cholesterol ester metabolism induced by beta-migrating very low density lipoprotein (β-VLDL) in J774 macrophages were studied. The cholesteryl ester content in the macrophages was increased by incu-

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