Abstract
The renal functions and the pathological changes in the biopsy meterial of 14 patients with acute glomerulonephritis were observed up to 2-6 months. The clinical finding was compared with urine protein, urine sediment, blood pressure and the pathological finding of the biopsy material, whereas the precise renal function (Fishberg's test, PSP-test, BUN, R.F.F., G.F.R.) was checked. There were two types of the glomerular lesion; one of them was a group who had the pathological changes in the glomerular capillaries and the other group had the changes in the Bowmann's capsule, tubules and interstitium in addition to the capillary lesion of the first group. No one showed hyalinisation and fibrinization. 1) Majority of the cases of which urine protein became positive at the 1st month following the onset of the disease belonged to the second group. 2) Majority of the cases of which blood pressure were beyond 150mmHg (systolic) or 90mmHg (diastolic) belonged to the second group. 3) No particular correlations between Fishberg's test, PSPtest and the pathological changes were found. 4) Majority of the cases of which GFR and FF were low belonged to the second group. 5) Some of the biopsy material showed the pathological change in the epithel of the Bowmann's capsule at the early stage of the disease.
