The Japanese Journal of Nephrology
Online ISSN : 1884-0728
Print ISSN : 0385-2385
ISSN-L : 0385-2385
Acute thrombocytopenia after intravenous infusion of radiographic contrast medium
YASUO KUDOHTOSHIAKI KIJIMAOSAMU IIMURA
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1991 Volume 33 Issue 9 Pages 885-888

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Abstract
Acute thrombocytopenia due to intravenous infusion of radiographic contrast media is extremely rare. We report the first such case in Japan. A 52-year-old male was admitted to hospital because of right ureteral stone. Two hours after drip infusion pyelography, the patient experienced chills and fever. It was shown that his platelet count had decreased abruptly from 233, 000 to 8000/mm3. Platelet associated immunoglobulin was not detected. An in vitro test for platelet aggregation by contrast media was negative. Following infusion of hydrocortisone, the platelet count recovered to a normal level within several days.
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© Japanese Society of Nephrology
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