Abstract
On the basis of ten cases of poisoned kidnies due to organic phosphorous pathologic study has been attempted. For confirming the organic poisoning activity of cholinesterase in the blood serum was examined with modified method of Michel. All cases revealed to be positive. These are deviled into three groups according to the life span calculated from the time of poison swallowing to the death. While the early group (a few hours of life span) showed marked vasodilation in the kidney, the middle and late group (several to over ten hours of life span) revealed more or less circulation disturbance which is characterised by pronouncing juxtamedullary circulation in sacrifying the subcapsular one. Also was noticed epithelial degeneration mainly of the proximal tubule running parallel to the deviation of the intrarenal circulation. The conclusion can, therefore, be drawn that the pathologic changes of the kidney encountered consist of parenchymatous attack as well as of the circulation disturbance within the kidney.
