The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
ISSN-L : 0021-5287
Case Reports
PATHOLOGICAL COMPLETE RESPONSE TO GEMCITABINE AND CISPLATIN CHEMOTHERAPY FOR ADVANCED UPPER TRACT UROTHELIAL CARCINOMA: A CASE REPORT
Masahiro MatsukiAtsushi TakahashiShuuichi KatouAkio TakayanagiYoshio TakagiKimio Kamata
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2013 Volume 104 Issue 1 Pages 33-37

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Abstract
A 61-year-old man was referred to our hospital with the chief complaint of right leg weakness. Abdominal magnetic resonance imaging (MRI) and computed tomography (CT) demonstrated a ureteral tumor and a neighboring massive retroperitoneal tumor in addition to retroperitoneal lymph node and right renal metastases. The tumor was diagnosed as upper tract urothelial carcinoma (cT4N1M1) by percutaneous tumor biopsy. As the patient achieved a partial response after three courses of combination chemotherapy with gemcitabine and cisplatin, he received total nephroureterectomy and lymph node dissection. The pathology showed no viable cancer cells, demonstrating a pathological complete response. He remains alive after 26 months with no evidence of disease.
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© 2013 Japanese Urological Association
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