1942 Volume 32 Issue 6 Pages 569-574,37
The blood sugar observations were made as before. But this time, the rabbits' liver glycogen was diminished by the injection of 5/10000 Strychnine nitrate sol. 1.0c.c. given in two times and the blood was taken 24 hours after the injection.
Experimental Results.
1) After injection of Adrenalin, hyperglycaemia was less marked in the rabbits which had received Strychnine than in those which had not received it, that is to say, in rabbits with an abnormal testicular function which had normal glycogen in their liver. But this result was most definite in the hypo-gonatic rabbits, not being any considerable change in the hyper-gonatic rabbits.
2) After injection of Morphin, hyperglycaemia was less marked in the rabbits which had received Strychnine than in those which had not received it, that is to say, in rabbits with abnormal testicular function which had normal glycogen in their liver. But there was a tendency for the hyperglycaemia to be more decreased in the hypofunctioning than in the hyperfunctioning rabbits' testicle.
3) After injection of Insulin, hypoglycaemia was less marked in receiving it, that is to say, in animal having normal liver glycogen. But this was rather more so in the hyperfunctioning than in the hypofunctioning rabbits' testicle.
4) The blood sugar content induced by the intravenous injection of Glucose was much increased in the rabbits which had hypo-functioning or hypo-fuctioning of the testicular hormone compared with the normal rabbits. But this hyperglycaemia was less marked after injection of Strychnine than before.
