STUDIES ON THE CHEMOTHERAPY OF CANCER OF URINARY BLADDER HISTOPATHOLOGICAL CHANGES WITH ANTICANCER DRUGS

Abstract

Carzinophilin, Mitomycin C, and Thio-TEPA were used to 32 cases of cancer of urinary bladder, and histopathological changes of tissue were studied. All of these cancers had their origin in transi-tional epithelium, and almost were discovered with haematuria in early stages and diagnosed by cystoscopy.
Anticancer drugs were administered in local or general, and the changes compared before and after administrations.
To 17 cases is general (Carzinophilin 7, Mitomycyn C 5, Thio-TEPA 5) and in local (Carzino-philin 7, Mitomycin C 6, Thio-TEPA 2).
In summary administration of anticancer drugs in general to cancer of urinary bladder which have their origin in transitional epithelium was not so effective, while local method obtained some effective changes, and Carzinophilin was most effective, then Mitomycin C, Thio-TEPA.