STUDY ON CHEMOTHERAPY FOR RENAL TUBERCULOSIS

REPORT 4. A HISTOLOGIC EXAMINATON OF THE TUBERCULOUS CAVITY-WALL

Abstract

In 9 of 19 cases with renal tuberculosis, on which speletomy was performed, a histologic examination was done on the cavity-wall removed at the operation.
All the cases examined were found to be in the “completion-stadium of caseous cavity” (Wildbolz): severe destruction of the renal tissue in the cavity-wall with slight or marked regeneration of the capillaries was observed.
Almost parallel relationship between the intracavitary concentration of ¹³¹I-Hippuran, which was secreted into the cavity after injected intravenously, and the degree of the capillary-regeneration was revealed in 8 cases. One case without the parallel relation was found to have an open cavity with high intracavitary concentration of ¹³¹I-Hippuran and with epithelial regeneration with poor regeneration of the capillaries in the cavity-wall.
Tuberculous bacillus was found in cavity-wall in only 1 case.