CUSHING'S SYNDROME IN AN 8-MONTH-OLD GIRL

PERPORT OF A CASE AND REVIEW OF THE LITERATURE, WITH SPECIAL REFERENCE TO THE ELECTRON MICROSCOPIC STUDY ON ADRENAL CORTICAL ADENOMA

Abstract

A case of Cushing's syndrome in an 8-month-old girl was reported, in which removal of the left adrenal cortical adenoma resulted in marked improvement of clinical anifestations. Review of the literature was presented with a discussion concerning clinical manifestations, diagnosis and treatments of Cushing's syndrome in infants.
Electron microscopic observations on cells of the adrenal cortical adenoma revealed, that though the cellular ultrastructures, as a whole, did not differ so much from those of the normal adrenal cortex, findings in mitochondrias were characteristic in their distribution, and in variable size and form.