MAXIMAL URINE OSMOLALITY
Hisao Takayasu, Akimi Ogawa, Koji Nakauchi, Akira Ueno, Hiroshi Nito, Takashi Umeda
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1967 Volume 58 Issue 4 Pages 363-368
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1967 Volume 58 Issue 4 Pages 363-368
Urine osmolalities following the Fishberg concentration test were determined in 192 consecutively admitted patients.
The following results were obtained.
1) A linear relationship was found to exist between the urine osmolality and the urine specific gravity, with a correlation coefficient of 0.7.
2) The first urine specimen following the test showed higher osmolality than the other two specimens in one fourth of cases.
3) The maximal urine osmolality following the test was not always reproducible.
4) A lower limit of the maximal urine osmolality obtained statistically in patients with normal renal function was about 700mOsm/kgH2O
A progressive decrease with age was found in the maximal urine osmolality.
5) The maximal urine osmolality was reduced in patients with lower urinary tract obstruction, with bilateral renal disease and with adrenal disease.
6) Parallel with the elevation of serum urea nitrogen, the maximal urine osmolality was lowered.
7) No distinct relationship was found to exist between the maximal urine osmolality and the PSP excretion. However, the maximal urine osmolality showed a tendency to decrease according as the PSP excretion became impaired.
8) The maximal urine osmolality was found to be lower after surgical procedure than before.
