EVALUATION OF THE DIFFERENTIAL RENAL TEST IN THE SURGICAL RENAL DISEASES

Abstract

1) Differential renal test with creatinine- and p-amino-hippuric acid (PAH) clearance was performed in 83 cases (normal: 11 cases, several surgical renal diseases: 72 cases). Seperated urine volume (UV) and urinary concentration of creatinine, PAH, Na, Cl, Ca, P, K, Mg respectively were estimated. The ratio of each of the separated urinary volumes, and creatinine- and PAH-clearance values was calculated in normal cases. Thus a chart was prepared (Table 3 in Japanese text).
2) In the cases of hydronephrosis U_PAH and C_PAH were reduced characteirstically on the affected side. The fact may be considered that the functional impairments are mainly due to the altermations of the renal tubules.
3) In the cases of upper urinary calculi (calyceal and pelvic calculi) without hydronephrosis the renal function is normal, whereas the case with hydronephrosis shows the same pattern of hydronephoris. In osmotic diuresis (loading of 8% urea solution), urinary calcium excretion from the affected side is definitely increased as compared with one from the unaffected side.
4) In the cases of renal tuberculosis the renal function is decreased severely in comparison with renal organic changes.
5) In the cases of movable kidney, even if urinary retention is shown in intravenous pyelography, the renal function remains almost normal.