STUDY ON THE RECOVERY OF THE COMPLETELY OBSTRUCTED KIDNEY IN DOGS

Part 1. Evaluation of the completely obstructed kidney using angiography in dogs

Abstract

Unilateral ureteral ligation was conducted on the 10th, 20th, 30th, 40th, 50th, and 60th day in order to prepare obstruction of the kidney. The study on the degree of recovery of kidney function was conducted using the angiographic method on 63 mongrel dogs both immediately after the ligation and two months after removal of the obstruction.
The results were as follows:
1. Vascular and excretory nephrograms taken immediately after the removal of the obstruction could be seen in all the cases in the 10th and 20th day groups, whereas the pyelogram could be seen only in the 10th day group.
2. Vascular nephrogram, excretory nephrogram, and pyelogram two months after removal of the obstruction could be seen in all cases in the 10th, 20th, 30th, and 40th day groups.
3. These results indicate that the time limit for the recovery from a renal blockade is 40th day blockade. Though the vascular nephrogram had the most sensitive reaction, it was not suitable as an indicator for the degree of recovery from renal blockade.
4. The caliber of the renal artery on the obstructed kidney side (r), its ratio to that of the opposite side (r/1), and its ratio to the caliber of the aorta (r/A) were all decreased gradually with the duaration of obstruction. And the recovery of the caliber two months after removal of the blockade observed in the groups with blockade shorter than 40 days.
5. The values in 40th day group determined immediately after removal of the obstruction were approximately 1.4mm, 57%, and 20%, respectively, which were equivalent to about 50% of the normal ranges.
6. Accordingly, the caliber of the renal artery is appropriate as the parameter to estimate the degree of recovery of the kidney function after removal of the blockade.