The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
DIAGNOSTIC SIGNIFICANCE OF ADRENAL COMPUTER SCINTIGRAM ASSOCIATED WITH LIVER SCAN AND SELECTIVE ADRENAL VENOGRAPHY
Teruhisa OhashiMasaaki MoriokaTeruaki AkaedaOsamu MorinagaYasuhiro KatayamaMotoyoshi TakataYosuke MatumuraTadao Niijima
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1976 Volume 67 Issue 6 Pages 389-401

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Abstract

1. Adrenal scintigram was performed for 4 patients with Cushing's syndrome due to ACTH excess, 4 patients with Cushing's syndrome due to unilateral adrenal adenoma, 7 patients with primary aldosteronism, 2 patients with pheochromocytoma and 3 patients with other hypertension, and selective adrenal venography was performed for 12 patients of them.
2. Preoperative determination of the site of the adrenal tumor was made in 6 of 13 patients by PRP, 7 of 9 patients by selective adrenal venography and all of 13 patients by adrenal scintigram, so that adrenal scintigram was proved to be very valuable.
3. It was successful to make early diagnosis for the site of small aldosterone-producing tumor within 1cm in diameter 2 to 4 days after intravenous administration of the tracer dose of 0.3 to 0.4mCi of 131I-6β-iodomethyl-19-nor-cholest-5(10)-en-3β-ol (131I-Adosterol) by means of an Gamma camera, aided by computer processing, i. e., subtraction, smoothing, leveling, associated with liver scan with 99mTcphytate on the same position.
4. Selective adrenal venography should be performed, unless PRP and adrenal scintigram were able to diagnose the tumor site.

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