A STUDY ON URINARY TRACT INFECTION

III. On the Immune Interferon Due to E. coli Infection in the Urinary Tract Report I. Natural Healing, Test Period and Dosage

Abstract

Interferon (IF)-producing ability of peripheral leukocytes from patients with E. coli was examined in the human embryonic lung cells-vesicular stomatitis virus system.
The leukocytes from the patients were found to produce IF upon contact with the specific antigen, whereas those from normal individuals were observed to have no such ability. The IF produced was identified as immune IF reported by Falcoff et al. on the basis of the following characteristics: species-specificity, lability to trypsin and acid treatments, and heat-stability. These data suggest that cellular immunity plays a certain role in urinary tract infection in man.