1978 Volume 69 Issue 5 Pages 539-542
Plasma and urinary carcinoembryonic antigen (CEA) assays were performed in 56 patients with urologic cancer and 20 controls. 93 plasma samples and 74 urine samples were determined by Roche Kit (Hansen Z-gel method). Plasma CEA level was elevated in 53% (17/32) in patients with bladder cancer and in 8% (2/25) in patients after treatment. Out of 8 patients with prostatic carcinoma, 2 patients had elevated CEA level. The incidence of plasma CEA positive cases in all urologic cancer was 22%. The normal range of urinary CEA was designated 0 to 3.0ng/ml. Urinary CEA level was elevated in 58% (15/26) in patients with bladder cancer and in 33% (4/12) in tumor free patients. However, all five infected urine from benign disease and 4 conduit urine showed high CEA level.
We thought that inflammation of urothelium as well as malignant changes caused production of CEA-like substance, so we concluded that the occurrence of elevated urinary CEA level, except urinary infection, was highly significant.
