STUDIES ON POLYAMINES OF THE CENTRAL NERVOUS SYSTEM, REPRODUCTIVE ORGANS AND URINARY BLADDER
Report 2. Effects of Spinal Cord Injury
1979 Volume 70 Issue 6 Pages 714-719
Details
1979 Volume 70 Issue 6 Pages 714-719
The changes of polyamines in the brain, male reproductive organs and urinary bladder after spinal cord injury were investigated by using male mongrel dogs. The polyamine determinations were made in dogs 1 week after transection of the spinal cord at the 11th thoracic vertebra.
The results are as follows:
In the male reproductive organs spermidine (SPD) contents in the prostate and testis were reduced markedly (P<0.05), while spermine (SPM) contents increased in the adrenal gland (P<0.01). In the urinary bladder, SPD increased in the neck portion, compared to those of the apex and body of the bladder (P<0.025). In the brain SPD increased markedly in the anterior hypothalamus (P<0.01).
