1981 Volume 72 Issue 7 Pages 900-909
Two cases of Thorotrast kidney accompanied with renal pelvic carcinoma were described. Although both of them had no obvious history of previous retrograde pyelography using Thorotrast, plain films of the abdomen showed dense opaque shadows characteristic of Thorotrast deposits.
One patient, 64-year-old male, died of disseminated metastases, and the other, 86-year-old male, of renal failure. Histologic examination of the autopsy specimens revealed moderately differentiated squamous cell carcinoma in the renal pelvis and other metastasized organs in the former, and transitional cell carcinoma with adenomatous parts of the renal pelvis in the latter where tumor formations has not been recognized at autopsy. Furthermore, the submucosal tissues in the vicinity of the carcinoma retained a large amount of black granules, which, on soft X-ray picture and microautoradiograph or gammaray spectra, or both, proved to be Thorotrast.
