IMMUNOCHEMOTHERAPY IN PROSTATIC CANCER
1981 Volume 72 Issue 8 Pages 973-978
Details
1981 Volume 72 Issue 8 Pages 973-978
Four patients with stage D prostatic cancer without prior hormone manipulation (3 patients with osteolytic bone metastasis and 1 patient with osteoblastic bone metastasis and cranial nerve involvement) and 1 patient with stage C prostatic cancer refractory to antiandrogen therapy, were treated with a combination therapy of Mitomycin C, FT-207, OK-432 and Hexestrol after castration.
This combination therapy brought about beneficial responses, such as calcification of osteolytic lesions (3/3) and disappearance of cranial nerve palsies (1/1) in the patients with stage D prostatic cancer, with slight side effects such as increased liver dysfunction (1/5) and anorexia (1/5).
