CLINICOPATHOLOGICAL OBSERVATION ON RENAL CELL CARCINOMA
SIGNIFICANCE OF HISTOLOGY OF THE TUMOR IN PROGNOSIS
1982 Volume 73 Issue 3 Pages 326-337
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1982 Volume 73 Issue 3 Pages 326-337
Seventy nine cases (51 males, 28 females) with renal cell carcinomas operated upon during the 17 years from 1962-1979 were histologically analyzed as to the postoperative survival rate. The overall relative survival rates 1, 3 and 5 years after the operation were 86.2%, 69.4% and 73.4%, respectively. On the grading based on nuclear atypia of tumor cells, 5 year relative survival rate was 87.5% in grade 1, 86.3% in grade 2 and 29.9% in grade 3. According to the tumor cell type, 5 year relative survival rate was 83.8% in cases of the clear cell type, 76.5% in the mixed type, 58.2% in the granular cell type and 0% in the spindle cell type. A significant difference in 5 year relative survival rate was also found between cases of carcinoma with the well circumscribed border (92%) and those with the poorly demarcated margin (35.3%). However, there was no significant prognostic difference in relation to the histologic types of carcinoma.
