1982 Volume 73 Issue 7 Pages 843-850
Twenty-eight cases of germ cell tumors of the testis were treated at the Department of Urology, School of Medicine, Chiba University from Jan. 1975 to Dec. 1980.
Stage I seminoma were treated with radiation after orchiectomy, and all 12 patients were tumor free at 6 months to 5 years and 1 month postoperativery. Non-seminoma, advanced seminoma, and seminoma with high HCG were treated with combination of various types of therapy including radiotherapy, chemotherapy, and retroperitoneal lymph node dissection or other surgery.
Retroperitoneal lymph node dissection was performed in six men after orchiectomy as the primary therapy. Three did not have metastasis, 2 had resectable metastases and 1 had unresectable ones. Among 5 completely resected cases 1 recurred locally and 4 relapsed with pulmonary disease. Therefore, retroperitoneal lymph node dissection as a primary therapy for non-seminomatous testis tumors seems to be inappropriate.
Combination of CDDP, BLM, and VBL as a primary therapy was applied to 3 high stage non-seminoma. All achieved complete remission. This modality of chemotherapy was observcd to be better than other combinations of drugs used.
