1983 Volume 74 Issue 3 Pages 401-408
Clinically unsuspected carcinoma of the prostate is sometimes found in subcapsular prostatectomy specimens.
We selected 25 patients who were diagnosed as benign prostatic hypertrophy clinically and had subcapsular prostatectomy. In these 25 patients, enucleated surgical specimen was examined histologically by means of the step-section technique. Five of the 25 patients were found to have prostatic adenocarcinoma. The serum acid phosphatase was not elevated preoperatively in these five patients. Three patients had well differentiated adenocarcinoma, one patient had moderately differentiated adencocarcinoma and one patient had poorly differentiated adenocarcinoma.
Age of the patients with prostatic carcinoma ranged from 72 to 87 years old with an average of 78.6 years old, and age of the patients without prostatic carcinoma ranged from 53 to 85 years old with an average of 69.7 years old.
Two of the patients with prostatic latent carcinoma had small lesions. Other three patients had large lesions.
Three patients with latent carcinoma had no treatment, one patient estrogens and castration, and the other patient had estrogens, castration and irradiation.