1983 Volume 74 Issue 3 Pages 418-426
Owing to the effective radiation-and chemotherapy, the prognosis of patients with seminoma has become fairly good. As far as the therapy is concerned, the unsolved problems have become scarce. However, patients with bad prognosis or recurrences are still occasionally encountered. In an attempt to obtain complete cure of all patients with seminoma, the authors studies and analysed the patients with bad prognosis.
A clinical analysis was made on 89 patients witn seminoma experienced at the Department of Urology, Yokohama City University and Department of Urology, Yokosuka National Hospital during the 17 years from 1963 through 1980. and the following results were obtained.
1. The five-year survival rate was 92.7% in all the cases with seminoma, showing 94.3% in stage I and 85.2% in stage II. The prognosis of anaplastic seminoma was bad and the five-year survival rate was 57.8%.
2. Deaths took place in 3 cases in stage I. Two of them died of anaplastic seminoma and the remaining one died of other disease.
3. Among the cases in stage II, one of 6 N1 patients developed lung metastasis, resulting in death. One of 6 N3 patients died of cancer and another is now living with recurrence.
Making reference to literature on the above results, the following was mentioned.
1. Anaplastic seminoma showed a bad prognosis, and the use of concurrent chemotherapy is necessary beside radiotherapy.
2. There are often caused failures in determining the stage, also determining the irradiation field, and in selecting the irradiation method, and accordingly a discreet precaution is needed.
3. To treat the bulky tumor of retroperitoneal lymphnode metastasis, the concurrent use of chemotherapy besides radiotherapy is essential.
