CLINICAL EXPERIENCE ON A SYNDROME OF RENAL FAILURE, GROWTH RETARDATION AND RENOURETERAL DYSMORPHISM

Abstract

Clinical experience on eight children with features of growth failure, renal insufficiency and renoureteral dysmorphism was reported.
Discussions as to etiology, pathophysiology and therapeutic modalities were made on this unique syndrome, whereby each feature is thought to be intermingled to affect one another.
A new theory of “hyperfiltration” for the genesis of progressive rena failure was proposed. The importance of total management besides uninary plasty was stressed.