1985 Volume 76 Issue 12 Pages 1889-1895
Clinical study of the bladder tumor was attempted to elucidate the prognostic factor and appropriate operation, bases on the 416 cases experienced in our department for the past twelve years. As far as the clinical staging was concerned, tumors were divided into low stage and high stage. As to the tumor grade and histological type, they were also classified as low grade and high grade. The parallel relationship could be found between tumor stage and tumor grade, while there were moderate numbers of cases with low stage-high grade or high stage-low grade.
Regarding as survival rate, five years survival rates of low stage and low grade groups were significantly higher than those of high stage and high grade groups, respectively. Five years survival rates of both low stage-high grade and high stage-low grade groups showed no significant difference. The cancer death rate of low stage-high grade group was almost the same as that of high stage-low grade one.
The analysis of cancer therapy clarified as follows: (1) Low stage-low grade group could be controlled by bladder preservation-therapy including TUR-bt. (2) Low stage-high grade cases were often necessary to undergo total cystectomy. (3) High stage-low grade group would be managed by radical cystectomy. (4) The treatment for high stage-high grade tumor should be performed by radical cystectomy, because the rate of cancer death in TUR cases was unacceptablly high.