1985 Volume 76 Issue 5 Pages 723-733
Determination of factors influencing the prognosis is important in the management of patients with urinary bladder carcinoma. A clinico-histopathological study was undertaken in 106 patients with infiltrating carcinoma in accordance with the General Rules for Clinical and Pathological Studies on Bladder Cancer.
The 5-year survival rate was estimated by the Kaplan-Meier method in relation to the clinical and pathological factors. The survival curves were comparatively analyzed by the generalized Wilcoxon test. The factors affecting the survival consisted of cystoscopic growth pattern, size, histological stage (pT), histological grade (G), intramural lymphatic invasion (ly), intramural venous invasion (v), histological growth and spread pattern (INF).
We then attempted to determine the significance of histopathological factors that were considered important, namely, pT, G, ly, v and INF. INF and pT were closely correlated to the survival.
Furthermore, the following formula was obtained for calculating the estimated survival months (M) on the basis of these 5 factors; M=58.1384-6.9006(pT)+9.8769(G)+3.1088(ly)+5.4930(v)-18.6684(INF). (R=0.7652, F=4.8047).
