1985 Volume 76 Issue 8 Pages 1201-1204
The presence of Thomsen-Friedenreich (T) antigen has been demonstrated in a variety of cancers, including bladder tumors. However, not many reports are available on this subject. We evaluated serum anti-T antibody titer in bladder tumor patients by enzyme linked immunosorbent assay (ELISA) and the following results were obtained.
1. Bladder tumor patients had depressed levels of anti-T IgM antibody.
2. Levels of anti-T IgG antibody in bladder tumor patients were significantly increased. (p<0.05)
3. No correlation was found between anti-T IgA antibody titers and the presence of bladder tumor.