1985 Volume 76 Issue 9 Pages 1386-1392
The effects of transcatheter embolization of the renal artery on the total kidney function were assessed in terms of changes in serum creatinine and blood urea nitrogen in patients with renal carcinoma. The patients were divided into two groups. One was those who received transcatheters renal embolization (Embolization group) and the other was those who underwent nephrectomy only (Non-Embolization group).
White blood cell counts and the blood urea nitrogen, serum creatinine, GOT, GPT, and LDH were increased more in the embolization group than in non-embolization group. The deterioration of renal function assessed by the increases in serum creatinine and blood urea nitrogen seemed due to the nephrotoxic action of contrast medium used during embolization. The increase in white blood cell counts might be the consequence of tissue necrosis. The increase in serum GOT, GPT and LDH might be the result of release of renal enzymes.
The results indicate that reduction of contrast media and adequate hydration are necessary for reserving renal function during renal embolization.
