1986 Volume 77 Issue 1 Pages 87-91
To evaluate tumor markers in renal cell carcinoma, plasma Fibrinogen, ACTH, Renin and Prostaglandins, and serum FSH, LH, Prolactin, Cortisol, PTH and Erythropoietin were measured in 25 renal cell carcinoma patients.
Plasma fibrinogen levels were elevated in 11 of 23 patients (47.8%). The elevation was more frequent (8 of 10 cases) in high stage patients. The elevated plasma fibrinogen levels were normalized after the curable nephrectomy. Plasma fibrinogen levels were significantly correlated with tumor stages.
Plasma prostaglandin F level were elevated in 7 of 16 patients (43.8%). The levels were elevated in 6 of 9 high grade patients (66.7%). Plasma prostaglandin F levels were obviously correlated with tumor grades.
No significant relationship between other parameters and tumor stage or grade were found in this study.