A CASE OF INVASIVE BLADDER CARCINOMA CURED BY COMBINED CISPLATIN AND RADIATION THERAPY

Abstract

An 81-year-old male patient visited our department in September 1983 because of gross hematuria. An invasive tumor of the bladder base was revealed on cystoscopy. The biopsied specimen was grade 3 transitional carcinoma of the bladder with prostatic invasion. The patient was given a trial of intravesical BCG therapy first. However, this trial was not effective on the tumor. In February 1984, the patient was treated by the combination of cisplatin and radiation. After two courses of cisplatin at an interval of three weeks with radiation of 5400rad, complete response was obtained for more than 18 months. No significant toxic reaction was noted.