1986 Volume 77 Issue 2 Pages 220-225
Clinical and pathological studies were performed on 37 autopsy cases of bladder tumor encountered at bur hospital from February 1965 to December 1983.
Histological examination revealed transitional cell carcinoma in 26 patients (70.3%), squamous cell carcinoma in 6 (16.2%), adenocarcinoma in 2 (5.4%), anaplastic cell carcinoma, primary malignant lymphoma and metastatic bladder tumor each in 1 patient each (2.7%).
Metastasis was noted in 30 of the cases (81.1%), and occurred frequently in lymph nodes (56.7%), liver (50.0%), bones (40.0%), lungs (36.7%) and colon (23.3%).
In 17 lymph node metastasis, the most frequent sites of occurrence were paraaortic nodes (11 cases), pelvic nodes (8 cases) and tracheo-bronchial nodes (5 cases). Eight cases which had lymphvascular invasion in resected tumor had distant metastasis at autopsy. A patient receiving curative operation died of metastasis of bladder tumor 37 months postoperatively. This case indicated the importance of long term clinical follow-up.
Only 27 of the deaths were attributed to carcinomatosis, other reasons including sepsis, uremia, pneumonia, fruminant hepatisis in 2 patients each, and acute myocardial infarction and gastro-intestinal bleeding in one patient each. Seven patients had multiple cancers.