1986 Volume 77 Issue 5 Pages 716-721
Invasive bladder cancer has been treated with multidisciplinary treatment including surgery (total or partial cystectomy), chemotherapy, radiation therapy and non-specific immunotherapy since 1977 in our Department. Thus far, 45 patients were treated in this manner. Among them, 26 underwent total cystectomy and 8 partial cystectomy. The rest 11 were in far advanced stage and surgical excision of the tumor was impossible.
1) Patient group (A), who underwent total cystectomy, showed 33% of 3 year relative survival rate and 25% of 5 year relative survival rate. Among them, 15 belonged to negative N and M categories, who showed 50% of 3 year relative survival rate and 39% of 5 year relative survival rate.
Seven patients with negative N and M categories showed tumor down staging and had favourable prognosis (85% of 5 year relative survival rate).
2) Patient group (B), who underwent partial cystectomy also showed good prognosis. Five out of 8 patients belonged to negative N and M categories, all of whom are alive without evidence of tumor (Mean duration; 54 months).
3) Patient group (C), who had disseminated disease did not show significant prolongation of relative survival rates, in spite of chemoimmunotherapy.