STATISTICAL OBSERVATION ON OUR BLADDER TUMOR REGISTRY

2. Patients' Age and Prognosis

Abstract

Studied in the present report were relations of patients' age at the first presentation to the survival rate and various clinicopathological findings of 1, 120 patients with primary bladder tumor treated during the 22 years from 1960 to 1982 at the university hospital of Tokyo Medical and Dental University and its affiliated hospitals.
The patients age' averaged 63 years ranging from 18 to 89 and peaked in the seventh docade (32.4%).
Five and ten-year acturial survival rates became worse with age except for those over 80. The 5-year survival rate of patients under the age of 60 years was 73.6% and significantly high when compared with 53.3% of those over 60 (p<0.001). Although survival rates generally decreased with age, the results appeared to be also attributable to the increasing incidence of high grade and high stage cancers in aged patients.
As to initial treatment methods, the incidence of conservative surgery (TUR and partial cystectomy) was almost unchanged at the level of 70% in any age group, total cystectomy was carried out most frequently in the patients in the sixth decade and other treatments such as irradiation, instillation, hyperthermia and hydrostatic pressure increased in patients over 70.
The incidence of senescent patients over 70 years of age increased year by year. The trend was obvious after 1976.
Four hundred and eleven patients died with mortality rate of 36.7%. Death from bladder cancer was most frequent (53%) followed by death from intercurrent diseases (16%). Cancer death was more common in the young than in the aged and death from intercurrent diseases increased with age.