IMMUNOPEROXIDASE LOCALIZATION OF PROSTATIC ACID PHOSPHATASE, PROSTATE-SPECIFIC ANTIGEN AND GAMMA SEMINOPROTEIN IN PRIMARY AND METASTATIC PROSTATIC CARCINOMA

Abstract

The immunoperoxidase techniques for prostatic acid phosphatase, prostate specific antigen and gamma-seminoprotein were used to evaluate autopsy materials from 9 patients with multiple prostatic metastases and 52 with primary prostatic carcinoma.
All specimens of primary and metastatic prostatic carcinomas stained positively.
Histochemical observation of prostatic acid phosphatase, prostate specific antigen and gamma-seminoprotein was useful for the detection of the prostatic origin of the metastases.