1986 Volume 77 Issue 6 Pages 988-994
The Tokai Urological Tumor Registry was founded in 1980 as a part of the educational project of Tokai Section of Japanese Urological Association. For 4 years from 1980 to 1983, 1474 cases (1185 males and 289 females) with primary tumors of the bladder were registrated in the registry. Among the 1474 cases, 1448 were selected from the registered cases for the present study. The discarded 26 cases included the followings: no treatment; 24, durign treatment; one, lack of details for analysis; one.
Curable treatment was performed in 1215 cases (84%), of which 320 (22%) received total cystectomy, and 895 (61%) were controlled without cystectomy. 77 (5%) cases were thought to be far advanced carcinoma at the initial visit to the hospital.
1299 cases (90%) were treated by surgery. Chemotherapy and radiotherapy were given in 590 (41%) and in 101 cases (7%), respectively. Chemotherapy and/or radiotherapy without surgery were effective in 26 tumors (3%).
Histologically, 1233, 32, 19 and 25 tumors were of transitional cell, squamous cell, adenocarcinoma and mixed cell, respectively.
Grading of 1233 transitional cell carcinomas consisted of 2%, G0, 27% G1, 40% G2, 28% G3 and 3% Gx. Incidence of superficial tumors (under T1) was 73% in the group of curable treatment and 22% in the non-curable treatment group.
After the curable treatment, reccurrence in the vesical cavity occurred in 171 cases (22%) of 785 cases who showed evaluable follow-up period after the treatment. Among them 20 received total cystectomy and the remainders (144 cases) were controlled by TUR. Distant metastasis developed in 44 of the 171 cases.
The total cumulative 3 year survival rate of this series was 73%. The 3 year survival rate of each therapeutic grop was 90% in conservative curable treatment, 67% in total cystectomy, 30% in non curable cases, and 3% in advanced cases.
