EFFICACY OF DRUG PROPHYLAXIS IN CALCIUM UROLITHIASIS

Abstract

We evaluated the efficacy of selective treatment in 134 patients with calcium urolithiasis. The recurrence rate was low in the cases of hypercalciuria treated with thiazide. Hyperuricosuric patients were also successfully treated with allopurinol. The recurrence rate was high in the cases of combined hypercalciuria and hyperuricosuria. Although, thiazide treatment seemed to be effective in these cases, allopurinol administration did not improve the rate of recurrence.
Problems in judging the efficacy of drug prophylaxis were discussed.