STUDIES ON CALCIUM OXALATE CRYSTALLIZATION PROPENSITY IN HUMAN URINE
2. Clinical Studies Uning An Aggregometer
1987 Volume 78 Issue 10 Pages 1701-1706
Details
1987 Volume 78 Issue 10 Pages 1701-1706
A previous study described that the calcium oxalate crystallization propensity might be established by means of the new method using an aggregometer in human urine. The purpose of the present study is to evaluate the clinical availability of this method on patients with calcium urolithiasis. The propensity of calcium oxalate crystallization was estimated by the turbidity max, which was described in the previous report.
The results were as foolows:
1) The turbidity max in calcium stone formers was significantly higher than that in healthy controls.
2) Although the turbidity max was well correlated with urinary calcium concentration in general, there was a difference in turbidity max between calcium stone formers and healthy controls with the same contents of urinary calcium. In addition, the ratio of turbidity max/calcium concentration in calcium stone formers was distinctly higher than that in healthy controls.
3) The reductions of 2 indices, turbidity max and ratio of turbidity max/calcium concentration, were observed in calcium stone formers treated with rice bran or citrate.
4) An aggregometric method is useful and convenient for evaluating calcium oxalate crystallization propensity and for estimating the efficacy of stone prevention.
