STUDY OF CREATINE KINASE-BB IN THE HUMAN MALE REPRODUCTIVE TRACT
1987 Volume 78 Issue 12 Pages 2071-2078
Details
1987 Volume 78 Issue 12 Pages 2071-2078
The BB isozyme of creatine kinase (CK-BB) activity is known to be abundant in human semen.
It is aimed in this study to investigate (1) the relationship between sperm count or sperm motility and content of CK-BB in the seminal plasm. (2) tissue content in the male accesory organ and testis, (3) immunohistochemical localization of CK-BB in the testis and sperm. There was no correlation between sperm count or sperm motility and CK-BB level. As far as the tissue contents are concerned, CK-BB could be detected in a large amount in the tissue of seminal vesicle, prostate and ampulla portion of vas deferens. A lowest amount of CK-BB was found in the testicular tissue. However, immunohistochemical study demonstrated CK-BB localization in the cytoplasm of the Sertoli cell as well as the spermatid cell in the testis. Moreover, reaction products could be depicted in the cap, neck and tail of the ejaculated sperm. It is concluded that CK-BB is an important enzyme for the movement of the sperm and for the penetration of the sperm into the ovum.
