1987 Volume 78 Issue 2 Pages 274-280
Continence mechanism was studied by urethral pressure profilometry during bladder empty and filling phases in “internal sphincter dogs”, i. e., female mongrel dogs whose external urethral sphincter had been removed three weeks before examintion. Urethral pressure at 0.5cm distal to the bladder neck showed no significant changes during bladder empty and filling phases. Urethral pressure at 1.5cm distal to the bladder neck during filling phase was significantly lower than that during empty phase. The avove difference of urethral pressure disappeared after propranolol administration. These findings indicate that relaxation of the internal sphincter seems to play some parts of continence mechanism.
