EARLY PHASE OF PROSTATIC CARCINOMA
CORRERATION BETWEEN TUMOR SIZE AND HISTOPATHOLOGICAL CHARACTERISTICS
1987 Volume 78 Issue 7 Pages 1185-1190
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1987 Volume 78 Issue 7 Pages 1185-1190
To elucidate the early phase of prostatic carcinoma, a retrospective study of 48 cases of incidental prostatic carcinoma was carried out. Tne biological significance of this disease was investigated on the basis of tumor size and histopathological features. A definite tendency was found between tumor size and its histological features. As the tumor progressed in size, there was a corresponding increase in its malignant potential. Namely, a large number of grade 1 (Gleason score 2-4) tumors were included in the group of less than 10mm in diameter, but a sufficient number of grade 2 or 3 (Gleason score 5-10) tumors measured more than 10mm in diameter. It is suggested that the early phase of prostatic carcinoma is devided into two biologically different groups. Management decision may be influenced by the classification of these groups such as stages A1 and A2.
