1988 Volume 79 Issue 3 Pages 495-500
We evaluated the bone mineral content (BMC) of 17 patients with idiopathic hypercalciuria, 22 patients with normocalciuria and 6 patients with primary hyperparathyroidism in calcium urolithiasis by the radiological assessment of bone density using microdensitometer (MD method). The BMC was significantly decreased in renal hypercalciuria with recurrent urolithiasis or primary hyperparathyroidism, but not in normocalciuria, renal hypercalciuria with initial urolithiasis or absorptive hypercalciuria. There were no correlation of the decrease of the BMC with the values of the fasting urinary cyclic-AMP excretion in renal hypercalciuria.
These results suggest that a long term negative calcium balance may be important component of disordered calcium metabolism of the bone in idiopathic hypercalciuria.
