1988 Volume 79 Issue 3 Pages 507-512
From January 1961 to June 1986, 705 patients with transitional cell carcinoma of the urinary bladder were treated at the Center for Adult Diseases, Osaka.
Four hundred and ninety-three patients underwent transurethral resection (TUR), 142 total cystectomy with urinary diversion, and 34 segmental resection. Five-year survival rates after TUR, total cystectomy and segmental resection were 76.8%, 59.8% and 46.2%, respectively. Ten-year survival rates were 61.2%, 49.4% and 41.6%, respectively.
Of 493 patients treated by TUR, 302 were G1, 155 were G2 and 36 were G3. five- and ten-year survival rates of G1 were 85.9% and 72.0%, those of G2 were 66.1% and 44.6%, and those of G3 were 39.8% and 24.9%, respectively.
Among the 493 patients, 227 were pTa, 196 were pT1 and 43 were pT2 or higher stages than pT2. Five- and ten-year survival rates of pTa were 91.5% and 78.5%, those of pT 1 were 75.5% and 60.6%, and those of pT2 or higher stages than pT2 were 49.0% and 22.0%, respectively.
Intravesical recurrence after TUR was significantly more frequent in patients with high grade and/or high stage tumors at first treatment.
Of 142 patients treated by total cystectomy, 13 were G1, 66 were G2 and 63 were G3. The five-year survival rate of G1 was 62.9%, that of G2 was 67.6%, and that of G3 was 51.7%.
Among the 142 patients, eight were pTis, seven were pTa, 37 were pT1, 32 were pT2, 19 were pT3a, 25 were pT3b and 14 were pT4. The five-year survival rate of pTis was 100%, that of pTa was 83.3%, that of pT1 was 64.3%, that of pT2 was 76.1%, that of pT3a was 58.4%, that of pT3b was 33.1% and that of pT4 was 25.9%.
In patients with G3 and deeply invasive carcinoma, survival of patients after total cystectomy was significantly better than those after TUR.
