The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
NORADRENALINE DENERVATION SUPERSENSITIVITY OF THE URETHRA IN PATIENTS WITH NEUROGENIC BLADDER
Yutaka YamashiroKosaku YasudaKoichi KamuraMasato MurayamaTakahiro WadaJun ShimazakiTakamichi Hattori
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1988 Volume 79 Issue 4 Pages 673-677

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Abstract

We studied the clinical usefulness of noradrenaline denervation supersensitivity test for the diagnosis of peripheral nerve injury of urethra.
Noradrenaline denervation supersensitivity test was performed in 43 patients with neurogenic bladder (13 patients with postoperative cervical cancer, 11 patients with postoperative rectal cancer, 11 patients with myelomeningocele in the lumbosacral area and 8 patients with cerebrovascular accident) and 9 patients with chronic prostatitis as neurologically normal controls.
Noradrenaline denervation supersensitivity was positive in 9 of the 13 patients with cervical cancer, 7 of the 11 with rectal cancer but no other patients.
Absence of noradrenaline denervation supersensitivity in patieats with myelomeningocele may indicate sympathetically normal urethras in those patients.
Therefore, we may conclude that noradrenaline denervation supersensitivity test is useful for the detection of sympathetic nevne injury of the urethra.

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© Japanese Urological Association
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