Abstract
The distribution of clinical isolates from patients with prostatitis and pathogenecity of the isolates were studied. A new method for measuring the bacteria-specific immunoglobulins in expressed prostatic secretion (EPS) was developed and used for the detection of local immuno-reaction against pathogenic bacteria in the cases with prostatitis. There were no cases. with increased antibodies specific for gram-positive cocci (GPC), indicating that the pathogenesity of GPC in bacterial prostatitis was doubtful. On the other hand, specific antibodies against gram negative rods (GNR) were elevated in all cases with acute prostatitis and changes of the antibody titers were correlated well to clinical courses. The present clinicostatistic and immuno-biological studies re-confirmed that E. coli was the main organism in uncomplicated bacterial prostatitis.
