The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
ISSN-L : 0021-5287
PRODUCTION OF GRANULOCYTE COLONY-STIMULATING FACTOR AND PARATHYROID HORMONE-RELATED PROTEIN IN SQUAMOUS CELL CARCINOMA OF THE RENAL PELVIS ACCOMPANIED WITH INFERIOR VENA CAVA THROMBUS
Kaoru NemotoIchiro MatsuzawaGo KimuraTaiji Nishimura
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2006 Volume 97 Issue 7 Pages 852-855

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Abstract

A 54-year-old man with general fatigue and lumbago was admitted for further examination of hypercalcemia and leukocytosis. CT showed a huge renal tumor and extension of the tumor thrombus to the inferior vena cava (IVC). Moreover, the serum granulocyte colony-stimulating factor (G-CSF) and the C-terminal of parathyroid hormone-related protein (PTHrP) were elevated. Under the diagnosis of advanced renal tumor, we performed nephro-ureterectomy and throbectomy. Pathological examination revealed squamous cell carcinoma of the renal pelvis. To our knowledge, this is the first case in Japan that of the simultaneous production of G-CSF and PTHrP in squamous cell carcinoma of the renal pelvis accompanied with IVC thrombus.

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