The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
ISSN-L : 0021-5287
COMPARISON OF CLINICAL RESULTS BETWEEN TUR-P AND HOLMIUM LASER ENUCLEATION OF THE PROSTATE (HoLEP) BASED ON THE INITIAL EXPERIENCE
Toshihide ShishidoKaori EnomotoNaoyuki FujitaAtsushi SuzukiKenjiro HayashiMasafumi NomuraNaoshi ItayaMitsuhiro TanboKazuyoshi WatanabeHaruhisa NodaTakatsugu OkegawaKikuo NutaharaEiji Higashihara
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Keywords: BPH, TUR-P, HoLEP
JOURNAL FREE ACCESS

2008 Volume 99 Issue 3 Pages 543-550

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Abstract

(Objective) We compared the surgical results between holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TUR-P) for the treatment of men with benign prostatic hyperplasia (BPH).
(Methods) A total of 87 patients with symptomatic BPH were analysed. HoLEP was performed on 46 men (mean age 68.2±7.5 years old) from December 2005 to February 2007, and TUR-P was performed on 41 men (mean age 69.2±7.3 years old) from April 2004 to March 2006.
(Results) Both groups were comparable in terms of age, pre-operative IPSS, QOL index, urodynamic study results and prostate volume. During operation, decrease in hemoglobin was less in the HoLEP group than in the TUR-P group (1.15±1.2 vs 1.91±1.3g/dl p<0.05). The operation time was significantly longer in the HoLEP group than in the TUR-P group (161.9±65.0 vs 118.3±36.9 minutes p<0.001). Mean resected weight was 29.3±13.3g (10-55) in the TUR-P group and 34.8±33.4g (5-148) in the HoLEP group (p=0.337). The catheterization period (52.1±29.6 vs 115.2±27.5 hour p<0.001) and hospital stay (6.6±2.3 vs 9.4±2.2 days p<0.001) were significantly shorter in the HoLEP group than in the TUR-P group. At follow up, Qmax, average flow rate and post void residual urine (PVR) in two groups improved significantly, and these parameters were not significantly different between the groups after 3 months.
(Conclusions) Both TUR-P and HoLEP were effective in relieving BOO. The estimated blood loss, a catheterization time and hospitalization were less or shorter in the HoLEP group. HoLEP may be a good alternative to the conventional transurethral electrocautery resection of the prostate for symptomatic BPH.

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© Japanese Urological Association
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